The anchors of the Booker T. sound were Steve Cropper, whose slicing, economic riffs influenced tons of other guitar players, and Booker T. Jones himself, who provided much of the groove with his floating organ lines. In 1960, Jones started working as a session man for Stax, where he met Cropper. Cropper had been in the Mar-Keys, famous for the 1961 instrumental hit "Last Night," which laid out the protoype for much of the MG's (and indeed Memphis soul's) sound with its organ-sax-guitar combo. With the addition of drummer Al Jackson and bassist Lewis Steinberg, they became Booker T. & the MG's. In a couple years or so, Steinberg would be replaced permanently by Donald "Duck" Dunn, who, like Cropper, had also played with the Mar-Keys.

Though they'd become established stars by the end of the decade, the group began finding it difficult to work together, not so much because of personnel problems, but because of logistical difficulties. Cropper was often playing sessions in Los Angeles, and Jones was often absent from Memphis while he finished his music studies at Indiana University. The band decided to break up in 1971, but were working on a reunion album in 1975 when Al Jackson was tragically shot and killed in his Memphis home by a burglar. The remaining members have been active as recording artists and session musicians since, Cropper and Dunn joining the Blues Brothers for a while in the late '70s.